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Age is one of the risk factors related to the onset of COPD and its interaction with tobacco consumption may be determinant for this disease.14,17,29 In our study, taking as a reference the onset of smoking before the age of 15 years and adjusting for cig/day, the risk of COPD is lower in those individuals who start smoking after the age of 15 years

It appears that Natural American Spirit cigarettes needed more drags, in fact 13, to fulfill this criterion, whereas the reference cigarette could be smoked with only eight drags

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Heating Element: Ceramic Coil

doi: 10.1016/j.jacr.2022.12.022 26